Brain and mental health are complex.

Sequoia Insilico Pvt. Ltd. · BioAI for brain & mental health

Connected intelligence for brain and mental healthcare.

SIPL brings clinical care, behavioural signals, neuroscience, genomics, and discovery into a responsible research framework for brain and mental health.

91%

HAM-D agreement, reported

500+

hospital assessments

₹50L+

GCE-III grant support, reported

Granted

Indian patent · PCT filed

Company-reported milestones. Assessment agreement is not a claim of diagnostic accuracy; supporting methods and records should be reviewed during diligence.

About SIPL

Deep research, translated into clinical intelligence.

Sequoia Insilico is a deep-science BioAI company based in New Delhi. Our work draws on bioinformatics, systems biology, neuroscience, and computational psychiatry.

We are building toward a richer understanding of brain health by connecting phenotype, biology, clinical context, and outcomes over time.

The SIPL architecture

One connected loop across care, integration, and discovery.

Clinical work informs research. New evidence creates better questions for care and study.

Care

Clinical assessment, structured information, and meaningful change over time.

Integration

Research and clinical information organised around real care and study workflows.

Discovery

Evidence from clinical practice and research informs the next set of questions.

A learning loop

Each stage informs the next.

01

Integrate

Bring permitted information into context.

02

Assess

Examine clinically relevant patterns.

03

Stratify

Explore meaningful patient groups.

04

Guide

Return useful context to professionals.

05

Monitor

Understand change over time.

06

Discover

Inform the next research question.

Science & evidence

Every model earns its place in care.

We treat each model and biomarker as a hypothesis to test. Evidence is examined alongside the intended use, the study context, and the limitations.

Reported clinical evaluation

91%agreement with clinician-rated HAM-D

Reported across 500+ assessments in a clinical validation collaboration with ABVIMS and Dr. RML Hospital, New Delhi. Agreement is not equivalent to diagnostic accuracy.

How we validate

Clinically grounded. Multimodal by design.

Literature groundingEthics reviewData qualityModel evaluationExternal validation

We aim to report performance with appropriate context, uncertainty, and limitations.

Intellectual property

Indian Patent No. 202511025669

WIPO PCT application in process, as reported by SIPL.

Research support

Grand Challenges India · GCE-III

₹50L+ equity-free support reported through BIRAC, DBT, and BMGF.

Recognition

Deep-tech startup

DPIIT recognition and a 2018 DBT–MoST award, as reported by SIPL.

Milestones are company-reported. Detailed methods, underlying records, and current IP status should be confirmed during diligence.

Evidence & IP details

BioAI for biopharma · Our horizon

The BioAI cornerstone for brain-health discovery.

The clinical intelligence we build for care today is laying the foundation for tomorrow's psychiatric research. These are the areas where SIPL and LifeBack® can help biopharma move faster — and where we're opening the conversation.

Discuss a research objective

Patient stratification

Explore clinically meaningful subgroups using behavioural, clinical, and biological context.

Digital biomarkers

Investigate repeatable behavioural measures and their relationship to clinical change.

Research direction

Pharmacogenomics

Research treatment response and tolerability in the context of individual biology.

Real-world evidence

Study longitudinal outcomes using appropriately governed clinical information.

Our precision framework

Precision care must be multidimensional.

Individual care depends on sound clinical interpretation and evidence that reflects the population it serves.

01 · Diagnostic precision

Understand the clinical picture.

Consider overlapping disorders, comorbidities, differential diagnoses, and disease trajectories rather than treating conditions as isolated labels.

02 · Population precision

Build for the people represented.

Evaluate relevance across demographic, genetic, linguistic, cultural, and socioeconomic diversity.

Who we work with

A collaboration platform for brain health.

Partnerships start with a clearly defined objective and an evidence pathway suited to the question.

Hospitals & health systems

Clinical workflows, research partnerships, and outcome measurement.

Clinicians & clinics

Evidence-informed tools that respect professional judgement.

Research institutions

Multimodal studies, validation, and scientific collaboration.

Biopharma & CROs

Patient stratification, trial design questions, and response research.

Genomics & diagnostics

Connect biological findings with phenotype and clinical context.

Implementation partners

Build practical pathways from research into real settings.

Responsible by design

Technology should help professionals see more clearly.

Clinical AI must be developed with clear purpose, careful handling of sensitive information, and accountability for how results are used.

Research ethos

Treat models as hypotheses. Evaluate evidence, uncertainty, and limitations.

Responsible data use

Use sensitive information with purpose, consent, and appropriate governance.

Human oversight

Keep qualified professionals responsible for interpretation and care.

Investors & strategic partners

A specialised BioAI platform connecting care and discovery.

SIPL is building at the intersection of brain health, multimodal research, genomics, clinical workflows, and biopharma.

Request an investor conversation

What to include

Tell us what you are exploring.

  • 01 Your organisation and area of interest
  • 02 The research or investment question
  • 03 What information would help a first conversation

Supporting documentation is shared directly where appropriate. Please do not submit personal medical information through the contact form.

The people behind SIPL

Research, clinical perspective, and engineering.

Meet the whole team
Dr. Anupama Singh

Dr. Anupama Singh

Clinical Research

Clinical researcher contributing domain expertise to SIPL’s responsible mental-health and clinical intelligence work.

Dr. Harsh Bhasin

Dr. Harsh Bhasin

Co-PI (ML Engineer)

Researcher and academic specializing in deep learning, algorithms, medical imaging, and computational mental health.

Tejwant Singh

Tejwant Singh

Junior Data Scientist

Researcher and data scientist working across machine learning, affective computing, multimodal learning, and computational psychiatry.

Coming soon

Advisory Board

We are bringing together experienced voices across clinical care, neuroscience, genomics, and biopharma. More details will follow.

In formation

Let's talk

Shape the future of brain and mental healthcare with us.

For clinical, research, genomics, biopharma, or investment discussions, tell us your objective and we will route it to the right team.

New Delhi, India

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