Sequoia Insilico Pvt. Ltd. · BioAI for brain & mental health

Connected intelligence for brain and mental healthcare.

SIPL connects clinical care, behavioural signals, neuroscience, genomics, and discovery in one responsible AI infrastructure. LifeBack™ is our flagship clinical platform for multimodal, clinician-supported mental-health assessment and longitudinal care.

GrantedIndian patent
97%HAM-D agreement
500+hospital assessments
BIRACgrant-backed validation

SIPL · FLAGSHIP PLATFORM: LIFEBACK™

Voice
Video
Clinical
Genomics
ONE
STRUCTURED
VIEW
Evidence-linked contextconfidence · uncertainty · longitudinal change

The proof, up front

Validated. Protected. Built in India. Ready for the world.

01

Patent protected

Indian Patent No. 202511025669 with an active WIPO PCT filing.

02

Validated in hospital

97% agreement with the HAM-D clinical standard across 500+ assessments.

03

Grant-backed

A BIRAC GCE-III grant deployed into product development and validation.

04

India-native

Engineered with interoperability and the Indian health stack in mind.

The SIPL intelligence architecture

Care, hospital, and discovery, connected in one system.

SIPL is building infrastructure that connects point-of-care assessment, hospital workflows, and governed scientific discovery. LifeBack™ is the clinical doorway into this larger ecosystem.

A SYSTEM THAT LEARNS

Every stage strengthens the next.

01UnderstandBring permitted information into one context.
02AssessIdentify clinically relevant patterns across signals.
03PersonaliseBuild an individualised view of risk and response.
04DeliverConnect insight to professional workflow.
05MonitorTrack meaningful change and outcomes over time.
06DiscoverReturn governed evidence to the next study.

LifeBack™ · SIPL flagship clinical platform

One evidence-linked view of depression, built from audio, video, and clinical signals.

LifeBack™ brings audio, video, and a structured clinical interview into a single assessment workflow. It organises and measures the signals; the clinician interprets the full picture and makes the care decision.

LifeBack™
CLINICIAN-SUPPORTED
ASSESSMENT FLOW

One patient. Multiple signals. One integrated assessment.

The modalities are considered together so no single audio, video, or questionnaire signal is treated as the diagnosis.

01

Audio assessment

Speech and voice features are analysed as behavioural clinical context.

Signal qualityClinical context
02

Video assessment

Facial and behavioural signals provide complementary information.

Signal qualityClinical context
03

Clinical interview & scales

A structured interview flow is combined with standardised measures.

Signal qualityClinical context
MULTIMODAL FUSIONEvidence-linked assessment contextconfidence · uncertainty · agreement
LIFEBACK™ / CLINICIAN VIEWASSESSMENT
Structured outputProfessional reviewReview all modalities together
AI

Professional interpretation required. LifeBack™ supports assessment and decision-making; it does not replace clinical evaluation.

GrantedIndian patent
97%HAM-D agreement
500+hospital assessments

Science & evidence

Research is not a phase. It is the foundation.

Every model, biomarker, and clinical pathway is treated as a testable scientific hypothesis that must earn its place in care.

97%

agreement with HAM-D across 500+ assessments at RML Hospital.

Clinically grounded

Research starts with clinical relevance and a defined intended use.

Multimodal by design

Evidence is examined across complementary biological, behavioural, and clinical signals.

Measured transparently

Performance, uncertainty, limitations, and subgroup behaviour are evaluated explicitly.

Human supervised

Qualified professionals remain responsible for interpretation and care.

Literature groundingEthics reviewData qualityModel evaluationExternal validation

Who we serve

One ecosystem. A distinct pathway for every partner.

01

Hospitals & health systems

Structured pathways, connected workflows, longitudinal monitoring, and outcome intelligence.

02

Clinicians

Clear, longitudinal, and explainable information that supports professional interpretation.

03

Researchers

Governed multimodal studies, biomarker investigation, and clinical evidence generation.

04

Biopharma

Patient stratification, clinical-development support, and real-world evidence built around the research question.

05

Genomics partners

Connect genomic information to clinically relevant longitudinal context.

06

Public health & investors

Responsible population programmes and a platform thesis connecting care with discovery.

BioAI for biopharma

Connect patient biology, clinical outcomes, and therapeutic discovery.

SIPL's multimodal intelligence infrastructure supports responsible research across discovery, clinical development, and real-world evidence.

Discuss a research objective
Biomarker researchdisease · progression · response · safety
Patient stratificationclinically and biologically meaningful cohorts
Clinical-study intelligencecharacterisation · outcome measurement · follow-up
Pharmacogenomic researchtreatment response · tolerability · variability
Real-world evidencegoverned longitudinal data beyond controlled trials

About SIPL

Building enduring intelligence for better brain health.

Sequoia Insilico Pvt. Ltd. is a deep-science BioAI company working at the intersection of clinical care, artificial intelligence, neuroscience, genomics, and life-sciences research.

Since its 2019 pivot from computational-biology services, SIPL has focused on making brain and mental health measurable, longitudinal, and precise.

Meet the team
Purpose

Turn fragmented information into useful, explainable intelligence.

Curiosity

Treat every model and pathway as open to testing and revision.

Responsibility

Keep clinical safety, privacy, and human oversight at the centre.

Integrity

Communicate evidence, uncertainty, and limitations with discipline.

Investors & strategic partners

A specialised BioAI platform connecting care and discovery.

SIPL is building intelligence infrastructure at the convergence of brain health, multimodal biomarkers, genomics, clinical workflows, and biopharma research.

01

Domain depth

Specialised focus on brain and mental health.

02

Multimodal context

Clinical, behavioural, biological, and longitudinal information in one record.

03

Ecosystem reach

Applications across care, research, genomics, and biopharma.

04

Responsible scale

Human oversight, validation, and transparent limitations built in.

WHY NOW, WHY SIPL

Validated, protected, India-native, and globally relevant.

97% HAM-D agreement500+ assessmentsFHIR R4 directionSeed round active
Request investor access

Responsible AI, security & trust

AI supports the professional. The professional leads the care.

01Purpose & consent

Define why information is used and the permissions that apply.

02Role-based access

Limit access to authorised responsibilities.

03Data protection

Apply appropriate safeguards to sensitive information.

04Auditability

Maintain traceable actions, versions, and review pathways.

05Human oversight

Keep qualified professionals accountable for interpretation and care.

06Model governance

Define intended use, validation, monitoring, and change control.

Security and compliance

Privacy, role-based access, auditability, and human oversight are designed into the platform architecture.

The vision

From one intelligence layer to a population-scale brain-health atlas.

SIPL is building toward an AI-native model of care where multimodal assessment, genomic and imaging data, EHR context, decision support, and longitudinal monitoring converge into one discovery-linked system.

Partner with SIPL

Let's build the next generation of brain and mental healthcare.

Hospital, research, genomics, biopharma, or investment: start with the objective and we will route the conversation to the right team.

Start a conversation New Delhi, India